Dissolution Enhancement of Fenofibrate by Solid Dispersion Technique

dissolution enhancement of glybenclamide by solid dispersion technique

Enhancement of Dissolution Rate of Efavirenz by Solid Dispersion Technique

Efavirenz is an HIV-1 specific, non-nucleoside reverse transcriptase inhibitor (NNRTI).It is an antiretroviral agent indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection, which is not soluble in water and lower absorption in gastric fluid. In order to improve the solubility and oral absorption of the drug in gastric fluid and to enhance its dissolution rate, soli...

Enhancement of dissolution rate of etoricoxib through solid dispersion technique

Etoricoxib, a non-steroidal anti-inflammatory drug, is used to Osteoarthritis, Rheumatoid arthritis and Acute Gouty arthritis. Etoricoxib is practically insoluble in water; hence present study was carried out to enhance dissolution properties of Etoricoxib through the preparation of Solid Dispersions using PEG 6000 as carrier at various proportions by using different techniques like Physical mi...

Enhancement of Dissolution Profile of Mefenamic Acid by Solid Dispersion Technique

The oral Bioavailability of BCS (Bio Pharmaceutical Classification System) class II drug with poor solubility and reasonable permeability is limited by drug dissolution. The purpose of this research was to obtain enhancement of the dissolution profile of Mefenamic acid (MA) using solid dispersion technique with hydrophilic polymers such as poly ethylene glycol (PEG), polyvinyl pyrrolidone (PVP)...

Liquisolid Technique for Enhancement of Dissolution Properties of Fenofibrate

The in vitro dissolution property of slightly water soluble Fenofibrate (FN) was improved by exploring the potential of Liquisolid system (LS). The in vitro release pattern of LS compacts and directly compressed tablets were studied using USP-II apparatus. Different LS compacts were prepared using a mathematical model to calculate the required quantities of powder and liquid ingredients to prod...